Endocrine Abstracts

Introduction: The long pentraxine-3 (PTX3) is a key component of humoral innate immunity that is expressed in various cell types during stress and tissue injury. PTX3 also acts like an oncosuppressor regulating tumor-promoting inflammation and it is implicated in tissue repair and autoimmunity. Autoimmune disease, tissue remodelling and oncogenesis often coexist in the thyroid. PTX3 role in thyroid disease is still unknown. Aim of the study is to evaluate if plasmatic levels o...

Introduction: The long pentraxine-3 (PTX3) is a key component of humoral innate immunity that is expressed in various cell types during stress and tissue injury. PTX3 also acts like an oncosuppressor regulating tumor-promoting inflammation and it is implicated in tissue repair and autoimmunity. Autoimmune disease, tissue remodelling and oncogenesis often coexist in the thyroid. PTX3 role in thyroid disease is still unknown. Aim of the study is to evaluate if plasmatic levels o...